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The aim of this research was to develop a measure of such secondary impairment.
The purpose of this investigation was to examine the efficacy of a new preschool oral language and early literacy curriculum package (Teaching Early Literacy and Language [TELL]) for children with developmental speech and/or language impairment (DSLI) either as a primary (e.g., specific to speech and/or language) or secondary impairment (e.g., developmental delay that includes DSLI).
In addition, following the initial hyperinflammatory response, immune cell apoptosis occurs, taking part in the secondary impairment of immune function.
The pathophysiological pathways behind this association are complex and progressive, leading to development of insulin resistance and secondary impairment of β-cell function.
In addition, secondary impairment of tissue occurs as a consequence of a prolonged pathological response involving chronic inflammation, microglial activation and astroglial scar formation.
Although POLG is a nuclear gene, clinical symptoms are related to a secondary impairment of mitochondrial DNA (accumulation of multiple mitochondrial DNA deletions, decreased mitochondrial DNA copy numbers or somatic mitochondrial DNA point mutations) in the affected tissues.
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Subsequently, serious secondary impairments (obesity, diabetes and cardiovascular problems) may eventually emerge.
The RSA-911 reports up to two impairments (the primary and secondary impairments as coded by the VR counselor who screened the applicant), and the ACS has a series of six disability questions that a number of studies have found to underreport disability.
Spasticity is a significant contributor to the secondary impairments impacting functional performance and participation.
In this model possible determinants of motor change include secondary impairments, personal and contextual factors (family ecology) and interventions.
Valvano [ 22] has recently described an intervention approach including functional training as well as prevention of secondary impairments by focusing on both activity goals and movement goals.
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