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SI value was calculated as the ratio of CC50/IC50.
SI value indicates selectivity of the sample to the cell lines tested.
It is important to note that GFW presents a much higher selectivity index (SI) value than the three mentioned chemotherapeutic agents.
Compound 10e also showed a higher SI value (SI = 49.0) than rociletinib (SI = 21.4), indicating its less side effect.
Among the target compounds, compound 7d exhibited the most potent potency against EBOV with an IC50 value of 5.29 μmol/L and an SI value of over 37.8.
Even after almost tripling the average SI value in 2007, national histology laboratories obtained a grade average of "C+" only, leaving room for improvement.
Moreover, the SI value of MAP is a power law function of the ionic strength of solutions but decreases with its increase.
The SI value (>69,000) of compound 11 was 60 times and 24 times higher than those of adefovir dipivoxil and lamivudine, respectively.
Obtained sPS showed a narrow molecular weight distribution (PDI ≈ 2), a high SI value (≥90%), and a high melting point (≈272 °C).
b: Selectivity index (SI) value equaled to CC50/MIC.
Let be the SI value, the decoded quantized index, the quantization step, and the reconstructed value.
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