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Control of blood pressure and risk attenuation: a public health intervention in rural Bangladesh, Pakistan, and Sri Lanka: feasibility trial results.
METHODS: We analyzed data on children aged 5-14 years who participated in the Control of Blood Pressure and Risk Attenuation (COBRA) trial in Karachi, Pakistan.
A nested cohort of 539 hypertensives aged 40 years and older from a community-living population in Karachi, Pakistan, followed up for 7 years in the Control of Blood Pressure and Risk Attenuation trial.
The Control of Blood Pressure and Risk Attenuation (COBRA) trial randomized 1341 hypertensive subjects in 12 randomly selected communities in Karachi, Pakistan, to 3 intervention programs: (1) combined home health education (HHE) plus trained general practitioner (GP); (2) HHE only; and (3) trained GP only.
We hypothesised that genetic variants associated with diabetes-related traits in Europeans would explain a similar proportion of phenotypic variance in a Pakistani population and could be used in Mendelian randomisation analyses.We used data from 2,131 individuals from the Control of Blood Pressure and Risk Attenuation Trial (COBRA) in Karachi, Pakistan.
Given that smoking is clearly related to education (Table 1) and smoking is an established cause of these cancers, this relative risk attenuation suggests strongly that smoking is a key intermediate factor on the education cancer pathway.
Similar(49)
Due to the risk of attenuation of the blood oxygen level-dependent response after severe seizure activity (Jayakar et al., 2002) all epilepsy participants were screened for a recent history of seizure clusters before conducting functional MRI scanning.
These precautions reduce risks of attenuation of mouse colonizing ability by any chance unfortunate choice of particular single colonies or passage in culture.
In addition, the deletion mutants used later in competition tests were recovered as pools from infected mice, to further reduce risks of attenuation.
Imaging pearl: Techniques to overcome this artifact often rely on patient respiratory coaching, as the command "take a breath in and hold it" can lead some patients to take a rapid deep inspiratory breath, increasing the risk of transient attenuation of the contrast bolus.
Traditionally, print media, TV and radio are the major transmitters of information from public health agencies to the public and play a large role in risk intensification and attenuation.
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