Sentence examples for Requires alteration from inspiring English sources

Metabolic response to oxygen availability requires alteration of the intracellular fluxes.

The appearance of new morphologies in multicellular organisms requires alteration of existing developmental pathways.

The evolution of novel forms in multicellular organisms requires alteration of the developmental mechanisms that shaped the earlier form.

Although a number of studies have reported the general features of transcriptome evolution [ 6, 23– 27], it is unclear whether transcriptome evolution requires alteration of the genomic response to acquire an adaptive state.

The homogeneous, or solution-phase, assays have the advantage that insoluble supports are absent (elimination of the problem with nonspecific adsorption) but rely on the strategy that requires alteration of the fluorescence properties of the label(s) on hybridization.

When tumor progression requires alterations in specific oncogenes (oncogene addiction), drugs that selectively block their products might slow tumor growth.

When tumour progression requires alterations in specific signalling pathways, drugs that selectively block them might slow tumour growth.

In the present study, except for T201 → S244, all the substitutions are radical, which is consistent with the fact that the evolution of new function requires alterations in the biochemical properties of the amino-acid sequence [ 67].

Mr. Hochberg's lawyer, Kevin J. Plunkett of Thacher Proffitt & Wood in White Plains, sent a letter to both school districts on March 19, demanding that they "effectuate the legally and morally required alteration of the school district boundary lines".

In interdependent and therefore tightly coupled systems, changes to one systems component will require alteration elsewhere in the system, therefore impairing the capacity of these systems to be changed.

In 2012, 173 of 523 presenters (33.5%%) disclosed relationships, with 49 having prior review (9.4 %), and eight required alteration.