With regard to the genetic literature for ADHD, our results failed to replicate a main effect of 5HTTLPR genotype with ADHD symptoms that has been previously reported [ 76- 78].
Even if QTL variances close to zero were estimated in single replicates as an effect of a weak data structure, especially in DYD models for short pedigrees, these estimates were not excluded from the analysis in all investigated situations.
Thus, despite replicating a null effect of context on gaze similarity, the gaze similarity measure was highly sensitive to changes in attention across the film clip.
However, the bronchial epithelial dysplasia seen in Adamtsl2−/− mice authentically replicates a specific effect of Adamtsl2 deficiency on target cells, which we have characterized here in detail, identifying glycogen as a major component of the enlarged vesicles.
26 27 For practical reasons, we focused on studies of the effectiveness of medicinal interventions and, after assessing the available studies, chose to replicate an investigation into the effects of statins on the mortality of patients with ischaemic heart disease (IHD) by Hippisley-Cox and Coupland (H-C&C).
25 As in our previous replication, we focused on studies of the effectiveness of medicinal interventions and after assessing the relevant studies that had been conducted in DIN, we chose to replicate an investigation into the effects of β-blocker treatment on cancer survival by Shah et al 22.
To replicate a prior main effect of the serotonin transporter gene promoter (5HTTLPR) genotype on cardiovascular reactivity (CVR) and explore caregiver stress as a potential moderator of 5HTTLPR effects on CVR.
Bump stocks use the recoil of semiautomatic rifles to replicate the effect of an automatic weapon, letting people hold down the trigger to fire multiple rounds rather than squeezing the trigger for each shot.
For the combined pedigree, 2000 replicates were performed with an effect of 0.32 and a frequency of 0.50 for the QTL in both grandparental populations, as the two pedigrees were reciprocal.
The authors concluded that: 1) if between-study heterogeneity reaches certain thresholds, it may not be practically possible to consistently replicate some true associations, no matter how large the studies are, and 2) replication sample sizes of 40,000 subjects or even larger are essential for generating sufficient power to replicate an association of small or modest effect size [28].
It fills a big, light and advantageous room on the ground floor of the Met, but it does not in any way seek to replicate the effect of a visit to the Hermitage.
