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Incident TB case-patients include those recently infected who progress rapidly to active TB and those with remote infection who progress after years of latency and are later diagnosed with active TB.
In the paediatric population, it is thought that Brodie's abscess often manifests in the vascular-rich metaphyseal region of long bones following haematogenous spread during a bacteraemia or remote infection [7, 10].
Comparably, the reactivation from the remote infection might be the main reason for the STR and EMB resistance.
Among the 20 subjects tested with the QFT-IT test, most LTBI (n = 17) were the result of a remote infection.
Although diagnosis and treatment of recently infected subjects deserves the utmost priority, because these subjects are at highest risk of developing active TB, detection of LTBI resulting from a remote infection may also be important.
Therefore, contrary to the findings of the TST, in cases of remote infection, the IFN-γ level did not increase during the short period of exposure to the antigen in the ex vivo IFN-γ assay at baseline.
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Long-term assays have also been shown to enhance detection of LTBI and to distinguish between recently acquired and remote infections [17], [18].
Ours is the first analysis of functional T cell subsets in epidemiologically distinct phenotypes of latent infection and now requires corroboration in a larger study population to ascertain whether significant differences in cytokine signature exist between recent and remote infections.
Postoperative infectious complications are usually classified into surgical site infections (SSIs) and remote infections.
As they state postoperative infectious complications can be separated into surgical site infections and remote infections.
The concept of 'brain-altering' remote infections is receiving increasing attention.
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