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"However, we must remember that there will be successes and interim failures as human trials proceed through the refinements necessary to achieve a successful human therapy.
Ambiguously aligned positions have been removed using Gblocks [ 65], with some manual refinements (necessary because of an inadequate stringency of Gblocks in the presence of missing data).
In addition, the powerful forces of the modelling fraternity have applied MD simulations to assess the stability of crystal structures and continue the refinements necessary to address key biochemical structures [ 54].
The Robinson-Foulds (RF) distance between two mul-trees T 1 and T 2 with identical label sets and matching label multiplicities, denoted by RF (T 1, T 2 ), is defined as the minimum number of contractions and refinements necessary to transform T 1 into another mul-tree isomorphic to T 2 [ 33, 34].
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But she projects none of the innate refinement necessary for Lily, who should mirror her name by embodying a rarefied mixture of delicacy, beauty and vivacious wit.
The unique aspect of this approach is the systematic consideration of design process decisions such as determining which couplings are important from a decision-making standpoint and the level of refinement necessary in the simulation models.
Although our questionnaire was aimed at assessing all types of physical activity, it lacked the level of refinement necessary to evaluate specific individual activities, such as walking.
One reason for the paucity of microarray-based diagnostic tests is that DNA microarrays require considerable effort to achieve the level of technical refinement necessary for diagnostic practice.
In addition to (74), the properties of the mesh-refinement necessary in current proofs of quasi-optimal convergence rates for adaptive boundary element methods [28,47] and adaptive finite element methods [13,44,45] are satisfied, i.e., the so-called overlay estimate and mesh-closure estimate are valid.
Energy performance contracts are a useful piece of the sustainability puzzle, but tailor-made refinements are necessary.
Further refinements are necessary in the design of this program to improve the experiences of guidance counselors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com