This was then used to refine the comprehension, options and wording of the DCE.
Human experimental data about vessel responses to triptans (Fig. 1) have refined our comprehension of triptan antimigraine effects and, indirectly, of the migraine mechanism.
The study of trans-Saharan medieval connections is another intriguing topic that has only recently begun to unveil its potential for refining our comprehension of past cultural trajectories in the whole African continent (e.g. Liverani 2005; Wilson 2012; Dowler and Galvin 2011).
These interviews assessed comprehension, refined the wording, optimized the response scales, supported the appropriateness of the recall period, and confirmed the content validity of the items.
ERPs analyses, an excellent tool to investigate the temporal and functional mechanisms supporting language comprehension, refined the behavioral understanding of the ACE.
The interviews were structured to evaluate the caregiver question/answer process, assess comprehension and refine question wording, optimize the response scales, confirm appropriateness of the recall period, confirm the content validity of the items, and confirm there were no missing concepts.
The survey was drafted and developed in English by the authors, then translated in to Tibetan, checked for comprehension, and further refined through pretesting by Tibetan team members.
The interview guide was further refined in terms of language and comprehension by pretesting the instrument with three healthcare professionals (OS, ENT, DAH) [ 17, 18].
In one study, terms were aligned with the existing Medical Dictionary for Regulatory Activities (MedDRA) and refined with input from patients, including comprehension testing within which patient-reported symptoms were categorised and defined [ 7].
This study teased apart the effects of comprehensibility and complexity on older adults' comprehension of warning symbols by manipulating the relevance of additional information in further refining the meaning of the symbol.
