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We further showed that fast-acting drugs that reduce the parasite load in vivo reduce presentation and prevent ECM death.
22 In the CNS, interferon-beta may also alter antigen presentation by monocytes and microglial cells to reduce presentation to T cells.
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Reduced presentation of Lpl at the lumenal side of capillaries could explain the phenotype of Col18a1−/− mice [30].
Both inhibitors markedly reduced presentation of CII to both T cell hybridomas.
There was a consistent trend towards reduced presentation in the infected BMDCs, although the effect was subtle (Fig. 5B).
Rituximab inhibits the B-cell function, thus reducing presentation of autoantigen to T-cells and theoretically secondarily preventing B-cell expansion and islet autoantibody production.
We demonstrated that exposure to live or heat-killed S. Typhimurium (HKST) led to reduced presentation of peptide and native Ag to type A T cells.
Infection of bone marrow-derived dendritic cells (BMDCs) with Salmonella enterica serovar Typhimurium (S. Typhimurium) reduced presentation of antigen to Type A T cells but enhanced presentation of exogenous peptide to Type B T cells.
These include reducing antigen presentation through reducing the activity of dendritic cells or promoting their tolerogenic phenotype, affecting the polarization of monocytoid cells, altering B cell function, decreasing chemokine gradients and reducing tissue-specific homing [ 24– 27].
DR. PATRICIA A MARYLAND: Since Cliff Barnes stole my word and my thunder here by sharing quite a bit about Ascension Health, I'll sort of reduce my presentation just a little bit, OK?
Strategies to reduce delayed presentation in this population must focus on education about symptoms of heart attack.
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