Sentence examples for Reduce alcohol intake from inspiring English sources
Thus, it was hypothesized that CeA Homer2b knockdown would reduce alcohol intake.
This is supported by recent studies showing that intracerebroventricular injections of NPY reduce alcohol intake in both alcohol-preferring (P) and high alcohol-drinking rats.
However, there was a clear genotypic difference in the capacity of effective doses of JNJ-16259685, MTEP and U-73122 to reduce alcohol intake under DID procedures (Figure 5) (Genotype × drug: F 4,80)=3.69, P=0.02).
More recently, sazetidine-A, which selectively desensitizes α4β2 nicotinic receptors, was shown to significantly reduce alcohol intake in a rat model.
Exercise advice was reported most frequently (74.6%), followed by advice to reduce salt intake (69.3%), change eating habits (61.9%), and reduce alcohol intake (43.5%).
These findings show that a combination treatment designed to target simultaneously serotonergic, dopaminergic, and opioidergic systems can reduce alcohol intake, even though the doses of the individual drugs in the mixture are relatively low and ineffective when given singly.
Interestingly, administration of a melanocortin 4 receptor agonist to mice (icv) reduced alcohol drinking [ 64], and administration of a melanocortin 3/4 receptor agonist to alcohol-preferring rats reduced alcohol intake in association with reduced food intake [ 65].
Compared to vehicle, tandospirone significantly reduced alcohol intake at 30-min (Fig. 2B), and 2 h (Fig. 2C).
Most experts believe it is an inevitable part of ageing, but say lifestyle changes, such as losing weight and reducing alcohol intake can improve levels and symptoms.
To assess for nonspecific effects of intra-CeA antagonist infusion, an effective dose of a particular antagonist for reducing alcohol intake was then examined for effects upon 5% sucrose intake during a 2-h session.
Despite no alcohol-induced change in protein expression, intra-CeA mGluR5 blockade reduced alcohol intake in both B6 mice and B6-129 hybrid mice, suggesting an increase in CeA mGluR5 function by a month-long history of binge drinking.
