The resulting model, recapitulating the essential features of in vivo neocortical development, can be used to construct in vitro models of cocaine-induced neocortical disorders and develop therapeutic strategies for the prevention of cocaine-induced impairment of brain development.
Before describing our solutions based on these methods, we recapitulate the essential features of the 10320/loc implementation based on handle records.
In view of the above information, we proposed a novel approach to assess whether the animal models recapitulate the essential features of human diseases for drug research.
Through exploring the relations between drug molecules and mouse disease models, our method was able to assess whether the corresponding model recapitulates the essential features of the human disease.
We evaluated mechanisms contributing to the adverse effects of chlorpyrifos (CPF) on DNA synthesis, cell number and size, and cell signaling mediated by adenylyl cyclase (AC) in PC12 cells, a neuronotypic cell line that recapitulates the essential features of developing mammalian neurons.
Choice of optimal scaffold material is essential for properly recapitulating the tissue microenvironment.
Owing to the essential role of the immune system in tumor eradication, preclinical animal models recapitulating the human disease in immunocompetent hosts are vital for assessing the efficacy of anti-GBM experimental therapies prior to testing in patients.
In real life, recapitulating the 19th century is both stupid and boring.
The sequence of cycles recapitulates the permeation process, while retaining the essential information on the permeation.
To test whether copper repression can recapitulate the loss of viability that an essential gene knockout causes, we placed P tcu-1 upstream of the essential gene, hpt-1.
As noted above, the model is already complex; we believe that the best approach is to construct a model with minimal complexity that both captures the essential biological steps and recapitulates the measured dynamics (as seen in Figure 3).
