There must have been other Grand Canyons in the lost world of the Great Unconformity, unknown and unexplored glories whose majestic waterfalls and gnashing rapids echo no longer from bare canyon walls.
T1-weighted volumetric images were obtained using a sagittal 3D magnetization prepared rapid gradient echo sequence (echo time/repetition time/inversion time = 2.9/2200/900 ms, dimensions of 256 × 256 × 208, voxel size of 1.1 × 1.1 × 1.1 mm).
Spin lattice relaxation times (T1) were measured using a rapid-acquisition rapid-echo (RARE-VTR) T1-map pulse sequence, with static TE (11 ms) and variable TR (150, 250, 500, 750, 1000, 2000, 4000, 6000, 8000, and 10000 ms) values.
A sagittal 3D magnetization prepared rapid gradient echo T1-weighted volumetric MRI (echo time/repetition time/inversion time 2.9/2200/900 ms, dimensions 256 × 256 × 208, voxel size 1.1 × 1.1 × 1.1 mm) was acquired.
Anatomic images were acquired using a high-resolution 3D magnetization-prepared rapid gradient echo sequence (60 sagittal slices, time echo [TE] = 4.6 ms, time repetition [TR] = 9.9 ms, flip angle = 8°, voxel size = 1 × 1 x 1 mm).
High-resolution structural 3D magnetization-prepared rapid gradient echo (MPRAGE) T1-weighted, turbo spin-echo (TSE) T2-weighted, and diffusion-weighted images were acquired for all infants for clinical review (sequence parameters can be found in Merchant et al. (2009)).
This included DTI, 3D T1 weighted structural imaging (magnetization prepared rapid gradient echo; MPRAGE), a Fluid Attenuated Inversion Recovery (FLAIR) sequence, a gradient echo (GE) sequence, and a dual echo (proton density/T2) sequence.
