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During these years of rapid brain development children are learning from their environments and interactions with adults and developing a foundation for their future school and life success.
"It is essential to their healthy growth and progress, particularly during periods of rapid brain development.
Psychotic disorders tend to emerge in late adolescence or early adulthood, during or after a period of rapid brain development.
The infant and toddler years represent a period of rapid brain development that sets the foundation for future growth and development.
Research is particularly clear about the strong positive effects of additional family income for young children, who are undergoing rapid brain development and may be especially vulnerable to the lasting effects of poverty-related stresses.
At this critical stage of rapid brain development, the observed alterations in the cellular organizational matrix of the entorhinal cortex strongly suggest that isoflurane (and LPS) are having a significant effect on the brain.
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The prevalence of poverty among the very youngest children means that during the first three years of life--a fundamental period of rapid brain growth and development--babies are deprived of the very resources they need to thrive.
Thus, we hypothesized that exposure of mice to UFP during early postnatal development—a period of rapid brain growth and differentiation should adversely influence CNS development by mechanisms identified as subserving air pollutant effects.
Additionally, exposure to benzo[ a]pyrene via breast-feeding in mice during the early postnatal period, corresponding to the rapid human brain development taking place during the third trimester, affected neuromaturation as measured by classic developmental behavior tests and to reduce expression of the serotonin receptor 5HT1A (Bouayed et al. 2009; Pan et al. 2009).
Chronic paraoxon exposure (0.1, 0.15, or 0.2 mg/kg subcutaneously) during a stage of rapid cholinergic brain development from PND8 to PND20 in male Wistar rats led to reduced dendritic spine density in the hippocampus without obvious toxic cholinergic signs in any of the animals (Santos et al. 2004).
Early childhood is a period of rapid myelination and brain development (6) and of increased sensitivity to insults affecting the brain (6, 7).
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