Quantitatively, the leaf transcriptome was the most strongly affected by a mild water stress (5151 entities differentially expressed) but quite surprisingly this response was not aggravated by a severe stress (4954 entities) (Table 1-B and Figure 2-B).
Such problems have become increasing important and quite general in genomics (identifying differentially expressed genes in microarray data), proteomics (finding promising protein marker from the mass spectrometry data), metabolics (selecting metabolite markers from NMR, GC-MS data), and other areas of computational biology.
The answer is, it's really important - and quite striking - because the liver differentially metabolizes fructose and glucose.
The consistent enrichment of genes with transferase activity in colored-cocoon specific and differentially expressed genes is quite intriguing.
The transcriptomic response 30 DPP is quite distinct as the majority of differentially expressed genes are increased at this time point, and they represent an enrichment of cellular pathways associated with tissue proliferation and repair.
Functional enrichment analysis using MIPS functional categories on the differentially expressed genes revealed a quite different response at transcriptome level compared to the pulse in the glucose phase.
Such definition is, indeed, quite specific and very different from a differentially expressed protein discovered as potentially related to some disease in a small set of sample.
In accordance with the fact that quite an abundant number of genes were differentially expressed, many gene networks were found to be affected in Hr6b knockout spermatids.
Although binding to cell-surfaces was quite similar at higher concentrations, keratinocyte proliferation was differentially affected.
We found that most of the genes (such as THY1, HELL, and ZP3) related to aging are similar to those previously identified in aging mouse ovaries [ 26], but some of the differentially expressed genes in pathways are quite different.
