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Prospective trials are warranted to compare adjunct treatment with dexmedetomidine versus standard benzodiazepine therapy.
Prospective trials are needed to evaluate the role of sedation with sevoflurane in this patient population.
Prospective trials should evaluate the impact of cholinergic stimulation with pyridostigmine on mortality.
Prospective trials would be needed to test this decision rule in actual use.
Prospective trials of chemotherapy in advanced ACC are limited, and the optimum regimen is unclear.
Prospective trials utilizing the SPAAT score are warranted.
Prospective trials are needed to further corroborate these results.
"But we need long-term, large-scale prospective trials to actually prove that".
These results should be further analysed in large prospective trials.
Randomised prospective trials are needed to confirm this.
There were no prospective trials (randomized or non-randomized).
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