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Recruitment will continue until the proposed sample size is reached.
These strategies will ensure the proposed sample size is achievable.
We would like to thank Dr. Tsai and others for mentioning our proposed sample size calculation.
There was one study that did not include a proposed sample size in the registry [ 10].
We conducted a power analysis based on the proposed sample size of 144 dyads.
bTrial stopped early after an interim analysis showed treatment effect too small to be demonstrated by proposed sample size.
This is a very conservative estimate of the minimum detectable effect size (MDEF) given the proposed sample size.
Considering the Design Effect (cluster sampling by buildings), we can accommodate an intracluster correlation coefficient (ICC) of up to 2.5% given our proposed sample size.
With α = .05 (two-tailed), the proposed sample (N = 36) would detect moderate effects between groups (d = .50) with over 95% power using a repeated measures F test.
Based on the proposed sample size, the study is sufficiently powered (80%) to detect only very large effects (d = 1.0 using Cohen's terminology [ 23]), assuming a 2-tailed test with alpha at 0.05.
Given the proposed sample size, we will be able to detect a relative risk of 0.5 with power ranging from 23% to 95% when the proportion reporting DV in the control arm ranges from 20%to50%0%.
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CEO of Professional Science Editing for Scientists @ prosciediting.com