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"pronounced distinction" is correct and can be used in written English
It is usually used to describe a clear difference between two things. For example, "The differences between the two products are marked, with a pronounced distinction in both quality and price."
Exact(3)
EPI shows a pronounced distinction between bone and adjacent musculature, but low spatial resolution limits the use of this technique [17].
Layer IV provided the most pronounced distinction as it was prominent and had a higher cell density in hOc4v when compared to FG1.
A consecutive canonical discriminant analysis with 2 discriminating dimensions (x- and y-axes in Fig. 8 B ) revealed a most pronounced distinction between the clusters within the first dimension (x-axis; 72% explained variance), complemented by the distinction within the second dimension (y-axis; 28% explained variance).
Similar(57)
Consonants written double in the Classical period were probably so pronounced (a distinction was made, for instance, between anus 'old woman' and annus 'year').
Although there is relative uniformity between the grading assigned by different investigators at the extremes of staining (grades 0 and ++++), variation is often most pronounced regarding the distinctions between the intermediate intensities of staining, such as between assigning a grade of + and ++ or between ++ and +++ for observed cellular density.
The widening of the ventricles are pronounced and sometimes the distinction between widening of ventricles and hydrocephalus of other reasons is difficult.
But these distinctions are unusually pronounced.
Such fine distinctions were less pronounced before 9/11, when Qadhi and others preached openly about the glory of Islam's early military triumphs.
(In case you've wondered about the distinctions, the city pronounced Yoo-stin is named for Sam Houston, a leader of Texas independence from Mexico, while the Manhattan street pronounced How-stin honors with altered spelling a Georgia delegate to the Continental Congress, William Houstoun. Texans no doubt believe that we're the ones who are saying it funny).
While Śaṃkara distinguishes between emotions and cognitions, his distinction is not as pronounced as that of the Nyāya-Vaiśeṣika philosophers.
This distinction might be particularly pronounced in cities with slums.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com