The availability of an effective therapy (α-galactosidase enzyme replacement therapy) has led to a great interest in Fabry's disease as a cause of stroke in young adults, however the risk of stroke remains substantial and management of conventional risk factors is important as well as prompt enzyme substitution therapy [60], [61].
Increasingly, sensitivity to the negative connotations of the label mentally retarded prompted the substitution of other terms, such as mentally challenged, developmentally disabled, and cognitively impaired, with the term intellectually disabled achieving wider currency in the 21st century.
You've got to give United credit, of course, but we've not picked up our men and we've been punished". County tackle Hibernian in next Sunday's League Cup final and McIntyre revealed midfielder Martin Woods "felt ill" at half-time, prompting his substitution.
Spurs were on the rack and the change in momentum prompted a double substitution from Pochettino, Kane and Townsend brought on for Nabil Bentaleb and Chadli.
About halfway through the first half, an injury to Di María prompted an early substitution.
The study by Peng and coworkers in Critical Care certainly contributes to that idea, even though the question whether relative adrenal insufficiency should prompt for treatment by substitution doses of corticosteroids remains unresolved.
Stephen Ireland swore at him after he rebuked him for failing to cut out the cross that led to Newcastle taking the lead in their 2-1 victoveroVillailla while Charles N'Zogbia, who was replaced by Emile Heskey in the substitution that prompted anger from the travelling fans, tweeted after the game: "First time in my life I'm not happy playing football".
But whatever prompted this last-minute substitution, it's a poor trick to play on Music Theater of Ventura County season ticket-holders, for it's difficult to imagine two other shows with so little in common.
This consists largely of gene substitutions prompted by natural selection, mutation, genetic drift, and other genetic processes that operate at the level of the individual organism.
