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We conclude that IGFBP3 is an inhibitor of tumourigenic phenotype and that ErbB2 may promote transformation, at least in part, through suppression of IGFBP3 expression and promotion of IGF1-dependent signalling.
The biology of migratory grasshoppers or locusts involves hormones that promote transformation of nonmigratory, solitary, shorthorned grasshoppers into gregarious hordes of locusts capable of causing great destruction.
Pomerleau V, Landry M, Bernier J, Vachon PH, Saucier C. Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions.
By further taking into account the inhomogeneity of the dislocation density, Gibbs energy contributions (driving forces) are derived that are sufficient to promote transformation as much as 100 °C above the Ae3.
More broadly, we aim to promote transformation and change in Palestinian society by, on one hand, challenging social attitudes and religious taboos about sexuality and gender and, on the other hand, advancing the social engagement and contributions of LGBTQ Palestinians through empowerment, education, and the development of leadership skills.
MEK activation through the MAPK signaling cascade is necessary for mammalian cell transformation, and constitutively active MEK mutants promote transformation of fibroblast cells [14, 15].
Similar(16)
To date, successes in novel metabolic pathway development have largely centered on short pathways and/or the recruitment of enzymes that promote transformations currently found in nature.
Identification of mis-spliced genes promoting transformation will uncover novel targeted therapies.
An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
Viswanathan, S. R. et al. Lin28 promotes transformation and is associated with advanced human malignancies.
Results showed that HA pretreatment of wastewater not only promoted transformation from POM to DOM, but also boosted biodegradability.
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