Sentence examples for Prolonging host survival from inspiring English sources
Stumpy forms are irreversibly committed to cell-cycle arrest in the bloodstream, thereby limiting parasite numbers and prolonging host survival.
Rather it functions to prolong host survival through a novel inflammasome-independent role likely through proper granuloma formation during chronic Mtb infection.
In mice, orthotopic implantation of mammary tumor cells lacking BST-2 increased tumor latency, decreased primary tumor growth, reduced metastases to distal organs, and prolonged host survival.
Also, treatment with micafungin significantly prolonged host survival in systemic and pulmonary murine aspergillosis when combined with nikkomycin Z (63, 64).
In the mouse model IL-10 reduces schistosome related liver damage and prolongs host survival [ 18], both of which are Th2-mediated, and in human S. haematobium and S. mansoni infections high IL-10 production has been associated with reduced schistosome-induced pathology(see [ 17] for review).
Specific active immunotherapy both with and without adjuvant did decrease tumor take and prolong host survival.
We hypothesized that treatment of infected mice would reduce the growth of Cn in the extracellular spaces of the lung, and prolong host survival.
The results presented in this study indicate that CD4+ CD25+ regulatory T cells, induced by rSSP4, suppress cardiac pathology and prolong host survival during acute T. cruzi infection in a specific way.
They found that the adoptive transfer of CD4+ CD25+ FOXP3+ T cells from rSSP4- (a recombinant T. cruzi amastigote derived protein) reduces cardiac inflammation and prolongs hosts' survival but at the same time, increases blood parasitemia and parasite loads in the heart.
The above survival study also indicated that host survival is prolonged by DC vaccination, despite its promotion of tumor cells with enhanced tumorigenicity in immunocompetent hosts (Fig. 4C).
We have successfully demonstrated the utility of this liquid-based screen to identify anti-infective substances that prolong S. aureus-infected host survival without affecting bacterial cell viability.
