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However, the extra fractionation procedure for PBMCs requires a prolonged period before RNA stabilization leading to significant ex vivo changes in gene expression profiling [ 49].
Finally, for 3 seroconverters, an MCV IgM peak was detected 1 2 years before the rise in MCV IgG titers, which suggests a prolonged period of infection before Ig class switching (patient 4).
Instituting "a prolonged period of barrenness before allowing childbirth" is God's "strategy" for "taming the dangerous female pride in her generative powers".
She says the reason for this is that NCDs are inherently chronic, so the effects of interventions targeting them require a prolonged period of time before tangible positive outcomes can be seen.
These patients may require a prolonged period of observation before being safely discharged from the ED.
The response immediately after cessation of stimulation included a short epoch of burst activity, followed by a prolonged period of silence before a return to LTS bursting.
Also, results may be more promising if there is not a prolonged period of hypoestrogenicity before treatment with oestrogens [ 199].
Due to the indolent course of the disease these symptoms often continue for a prolonged period of time before a diagnosis is reached [ 7].
We have not seen such a prolonged period of economic weakness since before even the 1930s.
What is clear, however, is that any referendum will invite a prolonged period of uncertainty, both before and after the event.
This results in a prolonged period of viral replication before the infected cell can be cleared by the immune system [12], [15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com