For example, the effect of HIV is more profound in the incidence of DLBCL, BL and central nervous system lymphoma (Engels et al, 2006).
Their responses illustrate a profound imbalance in the incidence of harassment: right off the bat, 53percentt of women say they have experienced it, versus 16percentt of men.
To the degree that these differences are not inherent to a patient's disease process, development and implementation of practice guidelines for the management of LEA could have profound effects on the incidence of LEA among Medicare beneficiaries.
These strains carry approximately 70 Mb and 23 Mb, respectively, long congenic BDIV-derived fragments spanning the corresponding loci that both exert profound effects on MPNST incidence and survival time compared with the parental BDIX strain.
Vaccination programmes against H. influenzae type b, S. pneumoniae (seven and thirteen valent) and N. meningitidis (serotypes C, A, Y and W135) have had a profound impact on the incidence of bacterial meningitis cases in many regions 6– 10.
This demographic shift is likely to have a profound influence on the incidence of HZ and PHN and may contribute to increased concern among European healthcare authorities; particularly if economic crisis and healthcare budget constrains persist in the long term.
12, 59 In addition, the development of effective drugs targeting the molecular mediators of the link between obesity and cancer may have a profound impact on the incidence and treatment of cancer.
Despite the administration of docetaxel, a drug associated with high incidence of profound asthenia, the asthenia noted in the present study was reduced compared to the docetaxel/RT study (12 vs 23% grade 2 asthenia).
More recently, a number of large studies found no increased risk of placenta praevia but supported an association with preterm 18 22 23 and very preterm delivery 24 25 The clinical implications of this are profound as reducing the incidence of preterm delivery, with its considerable associated problems, remains one of the most significant challenges in obstetrics.
First, these regimens may be optimised with the goals of reducing the incidence of profound grade 4 thrombocytopenia and neutropenia and of limiting the total dose of bleomycin, especially in patients with multiple lung metastases (for example those with the 'choriocarcinoma syndrome').
Thus, it is not known whether a more restricted diet might have a profound effect on breast cancer incidence.
