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Despite his creativity and sense of personal destiny, Frank is still bound to moments of profound helplessness and humility.
The stunned grief; the persistent, baffling and frightening sense that we can no longer work, sleep, breathe or love other people in serene peace; and perhaps most of all the profound helplessness and irrelevance that those of us who merely witnessed the tragedy experienced: these are the emotions that Joan expresses.
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When Americans living abroad watch a disaster unfold from afar, many struggle with a severe case of homesickness and a profound sense of helplessness.
Steeling himself against profound feelings of helplessness and fear, Dr. Smith quickly realized he had to become part of his son's treatment team as a patient advocate.
"The issue here is the profound amount of helplessness at the moment of impact," said Elana Newman, a psychology professor at the University of Tulsa specializing in responses to traumatic life events.
But sitting amid the rubble of their homes or sleeping in crowded tents, they have also faced a profound sense of helplessness, and a question with no easy answers: What next?
"Pelléas," Debussy's profound meditation on human helplessness, is from any observation point discreet, not to mention enigmatic, paradoxical and oblique.
Mitchell and Jessen proposed that torture could produce a state of "learned helplessness," or profound psychological trauma, and that this would lead to compliance with interrogators and divulgence of intelligence.
It takes the most profound loss and experience of helplessness to induce Pharaoh to let go.
But more than that, there remains a profound sense of anger, mixed with helplessness amongst most people.
Some doctors feel deep disgust towards disease and can have a profound fear of death and the helplessness that accompanies illness.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com