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"profound gratitude" is correct and usable in written English
You can use it to express a deep appreciation or thankfulness towards someone or something. For example: "I want to express my profound gratitude for all your help throughout this difficult process."
Exact(60)
Profound gratitude is expressed to all the former and current DTTBs who gave of their time to take part in this assessment.
People are expressing profound gratitude that the news media is offering non-stop coverage of Francis's every move.
I offer my profound gratitude to the dedicated researchers and conscientious clinicians who have made this possible.
The Trustees and staff of Greentree Foundation will always remember Emile with deep respect, profound gratitude, and abiding affection.
"The President expressed his profound gratitude for the courage and quick thinking of several passengers, including US service members, who selflessly subdued the attacker, " a statement said.
Being an object of gratitude is gratifying, of course, but it also turns out that feeling profound gratitude toward another is also a pleasurable emotion — humbling and inspiring.
The family wishes to express its profound gratitude to the Veteran's Administration Hospital in West Los Angeles, and the V.A. hospice facility in North Hills, California.
"I would like to express my profound gratitude to Dave for his enormous contributions to News Corp.," Mr. Murdoch said in a statement.
Hence the chateaubriand and the wine – why not? – and he was full of genuine wonder and profound gratitude for those who had nursed him.
"Belgian refugees express their profound gratitude to the Biterroise [Béziers] population for the welcome they received between 1939-1941," it reads.
"We want to express our profound gratitude to all of those who have supported Amanda and our family," the statement continued.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com