Sentence examples for Profound and sustained from inspiring English sources

Their pleasures are immediate and fleeting rather than profound and sustained, more like Broadway revues than three-act dramas.

"No individual in this country, on or off the Court, has had a more profound and sustained impact upon public policy in the United States for the past 27 years," it said.

In animal models, 5-HT6 receptor ligands of all functional types have been shown to decrease food intake when given acutely and chronically, to evoke profound and sustained weight-loss in obese animals, and concomitantly to improve a number of cardio-metabolic risk factors.

A disapproving article in the conservative National Review in 1984 said of him, "There is no individual in this country, on or off the Court, who has had a more profound and sustained impact upon public policy in the United States for the past 27 years". This of a man who could probably walk unrecognized down the main street of any city in America, save perhaps this one.

28 In summary, degarelix is associated with a rapid, profound, and sustained suppression of testosterone in patients with prostate cancer.

The rapid tophus resolution seen with pegloticase treatment may be explained by the profound and sustained lowering of urate levels.

In healthy postmenopausal women, a single subcutaneous dose of denosumab resulted in a dose-dependent, rapid (within 12 h), profound (≤84 %) and sustained (≤6 months) decrease in urinary crosslinked N-telopeptides of type I collagen (NTx).

A: You must practice constant iterations of something simple yet profound: create and sustain trust.

In a randomized, placebo-controlled phase-1 study in 49 healthy postmenopausal women, a single SC injection of denosumab caused a dose-dependent rapid (within 12 hours), profound (up to 84%) and sustained (up to 6 months) decrease in bone resorption (reflected by urinary N-telopeptide (NTX)) and was well tolerated.

Double-headed anionic surfactants could provide a profound group of efficient stabilizers of new template-mediated nanocarriers for effective encapsulation and sustained release of highly hydrophobic photosensitizers, and therefore their improved therapeutic activity in photodynamic therapy (PDT) protocols.

They did not go through the profound ideological conversion required so that a real two-state peace could be achieved and sustained.