There are of course a myriad of ways to do that, some obvious and quickly depleted, others profound and lasting.
A major text of early Kabbala was the 12th-century Sefer ha-bahir ("Book of Brightness"), whose influence on the development of Jewish esoteric mysticism and on Judaism in general was profound and lasting.
The impact of these breaches is profound and lasting.
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For students and teachers in the nation's second-largest school system, the repercussions of America's choice for president are likely to be both profound and lasting.
First and foremost, shaming or coercing parents into parting with their children or, worse, removing their children without consent (even when that's necessary), inflicts profound and lasting psychic wounds.
Two examples of this came last weekend, both with potentially profound and lasting consequences.
To harm a child sexually has profound and lasting effects and many argue that the law does not go far enough in punishing offenders.
The policy choices could have profound and lasting effects.
After all, silent protest can have a profound and lasting effect.
These revelations had a profound and lasting impact on public trust of internet privacy.
