He said Genentech began working on the plan a year ago, before criticism of Avastin's price mounted in the spring.
Despite the obvious strains under which CIT now labors — a plummeting stock price, mounting losses, funding woes and a loss of faith among some analysts — Mr. Peek says he wouldn't have done anything differently.
On the Colicchio plan, of course, prices mount quickly.
When prices mount into the hundreds of thousands of dollars a year, they impose a burden on patients and sometimes on employers and insurance programs that must pay most of the bill.
Analysts said they believed that inflation data for November, due out on Saturday, would show that price rises accelerated substantially in China from the 4.4 percent reading in October, and that inflation would remain higher than the authorities would like for some time, as wage pressures and commodity prices mount.
Which can only mean that as prices mount, so do the risks.
Pasminco, a large zinc and lead producer, filed for the equivalent of Chapter 11 bankruptcy protection, succumbing to low zinc prices, mounting debt and the damage from a failed currency hedging strategy.
But the basic goal was shared and simple — keeping the economy growing at a time when millions of Americans are losing confidence and cutting back in the face of falling home prices, mounting debt and rising joblessness.
Those portfolios have been a crucial means by which companies, banks and other financial institutions conceal hidden reserves of cash -- or, as in the last year of falling share prices, mounting losses.
As property prices mounted, smaller developers like Bruder were getting squeezed out.
