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This finding is in apparent disagreement with the well-known observations that phosphorylation of Ser518 (or the S518D substitution) can convert Merlin into its functionally inactive form (i.e., inactive in suppressing cell growth), presumed via certain direct, phosphorylation-induced conformational changes to the full-length protein.
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Patients with presumed transmission via injection drug use had higher rates of all causes of death than other risk groups, particularly deaths from infection, liver disease, and substance abuse.
> -wrap-foot> The association of presumed transmission via injection drug use (compared with MSM) with AIDS death was stronger in subsequent years of ART (HR, 1.5 [95% CI, 1.2 1.9]) than the first year (HR, 1.1 [95% CI, 0.9 1.5]).
Patients with presumed transmission via injection drug use had persistently high rates of liver-related death, and persistently higher rates of both AIDS and other non-AIDS causes of death.
Furthermore, flies heterozygous for the EY05103 P-element insertion (iPLA2-VIA), with presumed 50% gene activity only, did not display reduced survival (Fig. 1D and Supplementary Fig. 1A).
By trapping the reaction intermediate, the reaction mechanism under high pressure CFC-12 at a Pb electrode was presumed to proceed via dimerization of difluorocarbene.
In Sweden and Austria, by contrast, the default choice is to be an organ donor via "presumed consent," meaning people have to explicitly opt out if they do not wish to participate.
One of the important anti-apoptotic effects of NO is presumed to occur via its ability to react with non-heme iron complexes (FeLn) to form FeLnNO.
Each of the four proteins was tagged with a triple HA epitope at the C-terminus and expressed to the presumed endogenous levels via homologous recombination in the TbTLK1 RNAi cells.
TbTLK1 tagged with a triple HA epitope at its C-terminus was expressed to the presumed endogenous level via homologous recombination in the four clonal RNAi cell lines depleted of TbKIN-B or the three CPC subunits.
Errors in synthesis are presumed to occur via nucleotide misincorporation by Taq polymerase under conditions optimized for mutation [ 6].
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