Sentence examples for Poor safety profile from inspiring English sources

Systemic corticosteroids are often accompanied by a poor safety profile characterized by multiple adverse effects, such as fluid retention, hypertension, hyperglycemia, greater susceptibility to infections, osteoporosis, mood changes, and psychosis [5].

Blood transfusion should be reserved for those who are cardiovascularly unstable, due the relatively poor safety profile, lack of long term efficacy, and cost.

Chlorproguanil-dapsone+artesunate in Rwanda had a poor safety profile in G6PD deficient individuals most likely as a result of dapsone induced haemolysis.

CD+A showed a poor safety profile in individuals with G6PD deficiency most likely as a result of dapsone induced haemolysis.

The combination abatacept-etanercept study described above [ 31] confirmed this poor safety profile.

In addition, the combination of sunitinib and IFN- α was studied in a phase I trial and showed no evidence of a therapeutic synergistic effect and displayed a poor safety profile (Motzer et al, 2009).

This may be due to their beliefs that these medications are less effective compared to diet and exercise, and with poor safety profiles.

However, in the present study, it was found to have a poorer GI safety profile than celecoxib in patients with RA in terms of numbers of GI events and in terms of numbers of systemic and overall AEs, which were almost twice as frequent in the pelubiprofen group.

Non-pharmacological techniques have shown good results in SUNCT and SUNA but, since they have been tried on a small number of patients, the reliability of their efficacy is poor and their safety profile mostly unknown.

Early prokinetic agents, such as cisapride, display poor selectivity for their target receptor, 5-HT4, also interacting with hERG channels and, as a consequence, have a poor safety and benefit/risk profile.

Dual/Multi-targeting agents are beneficial for solving limited efficiencies, poor safety and resistant profiles of an individual target.