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In 1994, he and his co-workers performed a pivotal experiment that showed mice with cancer had been cured by the treatment.
This was an early pivotal experiment in EC miRNA biology.
Since the pivotal experiment by Orò [ 9] on the synthesis of adenine from HCN, numerous studies were devoted to assess the role of this compound in the origin of primordial nucleic acids [ 10].
The pivotal experiment performed by Woods et al. (4) in the late 1970s showed that intracerebral infusion of insulin in baboons reduced food intake and body weight and paved the way for intense scientific investigation over subsequent years by highlighting the key role of insulin at the central nervous system (CNS) level.
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We are indebted with Prof. Gianluigi Condorelli to permit the pivotal experiments of qPCR with miRs.
The Soviet Union — "one of modern history's pivotal experiments," in the weasel words of NBC's Olympics coverage — existed for seven miserable decades.
She began using human rather than animal cells, and in a set of pivotal experiments, she showed that her system could flag pharmaceutical compounds that might pose a danger to people.
In the past year and a half in the Harland Lab, Postdoc Amy Shyer says that Grant Schroeder has "designed and successfully carried out multiple pivotal experiments in the lab — one earned our paper a chance to be reviewed in a top journal, and the other formed the basis of an NIH grant". Schroeder will be a co-author on the paper set to be published in Science.
However, certain pivotal experiments done exclusively on C57BL/6J in the past should be validated on a progeny of an F1 cross with a distant strain, to verify that these discoveries do not belong to "parallel universes" of Black Six biology.
The pivotal experiments supporting the AGM's role as an autonomous source of dHSCs includes short-term ex vivo organ culture of the AGM, fetal liver and the yolk sac [ 63].
This result (i.e. the induction of Bet v 1-specific IgG without inclusion of Bet v 1-specific T cell epitopes in the vaccine) can be explained according to the hapten-carrier principle described by the pivotal experiments of the Nobel laureate B. Benacerraf that led to the discovery of T cell-dependent antibody production 2, 3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com