To pinpoint loci under positive selection, we calculated the XP-EHH statistic between Holstein and Hanwoo population groups.
For example, approaches such as genomewide scans for selection, association mapping or quantitative trait loci (QTL) mapping can pinpoint loci of relevance for local adaptation of the target population (Steiner et al. 2013), with the potential to conserve evolutionary processes – a long sought after goal in conservation biology (Crandall et al. 2000; Fraser and Bernatchez 2001).
In addition, our integrated analysis of genomic and transcriptional profiles pinpoints loci and genes with altered copy number and expression, providing a rich source for discovery and future characterization of new breast cancer genes.
However, sifting through the constellation of SNVs to pinpoint pathogenic loci (regions and positions) is a challenging task.
Formal theory complements informal, experience-based theory, helping to define areas of dysfunction in healthcare systems, pinpoint their loci, and identify their possible mechanisms.
Classically, microsatellite markers have been used for linkage analysis, and now millions of dimorphic SNP markers can be used to provide higher resolution in order to pinpoint candidate loci [ 8].
These maps have helped to pinpoint the loci of some important agronomic traits [ 25- 27], but they are sparsely populated and the different markers make them difficult to compare.
The main goals of our current work were to assess the feasibility of longitudinal data as an intriguing resource in GWAS, pinpoint associated loci and genes that contribute to the phenotypic variability and longitudinal trend in egg weight, and provide valuable insights into the genetic basis of longitudinal egg weights.
In three families with SSINS, Ruf et al. [ 9] were able to pinpoint a locus on chromosome 2p12-p13.2, and also demonstrated clear evidence for genetic locus heterogeneity upon examination of ten additional families with SSINS.
According to claims made by supposedly respectable neuroscientists, reported by supposedly respectable newspapers, it is possible actually to pinpoint the locus of love, wisdom or whatever as parts of the brain that "light up" under functional magnetic resonance imaging (brain scans).
I pushed him harder If he had to pinpoint the locus of Miami noir, where would it be?
