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The unstable stacking fault energy barriers for slip by far exceeded the transformation transition state barrier permitting transformation to occur with little irreversibility.
This great difference in dose energy supply from that of the tumor allows tumor growth through the phenomenon of transmutation that permits transformation of elements in live organisms [9 s].
Therefore, the largest permitted transformations included, for example, the addition of a substituted ring to a compound or the replacement of a five- or six-membered ring with a substituted condensed two-ring system (with a maximum of 13 atoms).
While loss of p53 alone is sufficient to circumvent NPM-ALK-induced senescence and permit cellular transformation, sole loss of Rb permits continued proliferation but not transformation due to p53-imposed restraints.
Annealing time depends on section thickness and should be long enough to permit complete transformation to β phase, while it should also be held to a minimum to suppress the grain growth of β phase (Donachie 2000; Ivasishin et al. 2002; Davis 1995; Borisova et al. 1975).
Samples reading below the standard curve were reported as one-half the value of the lowest detectable standard to permit log transformation of the data for statistical analysis.
In addition to the double mutation of the NF1 gene, additional genetic alterations also seem to be required to permit the transformation of benign PNF into MPNST.
Evidence suggests that mutated p53 can lead to genomic instability and permit malignant transformation of previously non-cancerous cells (Finlay et al, 1989).
The oligonucleotide RpoB1UP is the same as the upstream rpoBF1 but with a DNA uptake sequence (in lower case) that was added at the 5´ end to permit DNA transformation (7 ).
The acquisition of a Cbr-unc-119 mutation from a genetic screen provided a selectable marker to permit ballistic transformation and generation of fluorescent reporter strains (Zhao et al. 2010).
The technique permits the transformation of the problem, initially non-deterministic, into two independents deterministic sub-problems.
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