Sentence examples for Paramount significance from inspiring English sources

He described the video as "of paramount significance".

To the Pythagoreans (c. 500 bce), numbers were of paramount significance; everything could be explained by numbers, and numbers were invested with specific characteristics and personalities.

Calling the current development one of "paramount significance," the department estimated that the national income for the year would be at least $60,000,000,000, regardless of whether industry as a whole is shown to have operated at a profit or loss.

Lighting was of paramount significance to Belasco, a producer, playwright and all-around showman who was known less for the quality of his taste in dramatic literature than for his commercial success and dedication to a kind of surface realism that allowed him to indulge his near-maniacal attention to detail.

This is a cornerstone event of paramount significance.

Therefore, accurate estimation of PV parameter can be of paramount significance for efficient PV model design.

It is emphasized that the importance of preference-based multi-objective optimization is of paramount practical significance and preferences must be incorporated in many-objective optimization, where obtaining a representative subset of the entire Pareto front is less likely.

Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance.

Taken together, these findings may be of paramount clinical significance: these small molecule inhibitors inducing p53 reactivation could reduce the dose of cisplatin required in the clinical setting, thereby minimizing the potential adverse effects of cisplatin chemotherapy in HNC patients.

That is because the issues that we think to be paramount often lose significance during a candidate's term in office.

Detection and diagnosis of faults in cement industry is of great practical significance and paramount importance for the safe operation of the plant.