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Marianne Gasser, head of the International Committee of the Red Cross in Syria, was quoted by Agence France-Presse as saying that the hospital strikes filled her with "overwhelming despair". "I think about the people who died, and keep dying, again and again.
I dreamed I had somehow become the president of Kenya, and this filled me with overwhelming despair.
Sarah and I hugged her, trying, as we have both done all our lives, to protect her from her overwhelming despair.
"We feel overwhelming despair and sorrow, but we know we have to try to somehow cope and continue for Paul," she said.
At the time, I would have insisted that my rituals of self-abuse – drinking, pills, the impulse to put my body in danger in ways I now know were deliberate – were merely efforts to escape; that I was contending, however clumsily, with the overwhelming despair at the absence of God.
He knew that he was in a fragile state, but, at the loss of her, he had the brief feeling that he had left his body, a sense of such overwhelming despair that he wanted to obliterate himself from the earth.
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Plath, who battled with depression throughout her life, died by gassing herself aged just 30, seemingly overwhelmed by despair living with two tiny children through a bitterly cold London winter.
Parents who experience only negative affect are more likely to be overwhelmed with despair and relinquish their initial goals related to their child's care without generating any new goals.
People who don't have the honor that you and I do of seeing the world in this way often ask me how I keep from becoming overwhelmed by despair and pessimism.
Physical hardship and moral despair overwhelmed the society.
And she worries that those who are helping the refugees who are already tired and overwhelmed now feel despair, and wonder: why am I doing this?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com