Sentence examples for Optimize flux from inspiring English sources
The carefully adjusted expression level of individual components of the pathway is important to optimize flux and to avoid the accumulation of toxic intermediates.
CO2 inversions are performed for 2001 2012 to optimize fluxes from 84 regions of the globe using the JAMSTEC's atmospheric chemistry-transport model (ACTM) and CO2 observations from 66 sites taken from GLOBALVIEW-CO2 (2013) data products (Ref. Saeki et al. 2017 for more details; Thompson et al. 2016).
Aiming at minimizing the side effects of drug targets, this model does not need to determine biological objective functions for optimizing flux distribution.
To optimize the flux of LE-μ+ at PSI a new, dedicated surface muon beam line has been designed.
This review will describe various strategies and examples of applying protein design to pathway engineering to optimize the flux through the pathway.
Metabolic engineering has made great strides in developing tools to optimize the flux through a target pathway, but the inherent characteristics of a particular enzyme within the pathway can still limit the productivity.
To optimize carbon flux through gene deletion or gene amplification is one of the key technologies for production of substances based on fermentation.
Synthetic promoter libraries and a range of engineered constitutive promoters of varying strengths have been created (Alper et al. 2005; Hammer et al. 2006) and could be used to fine-tune the expression levels of all enzymes in a pathway in order to optimize metabolic flux.
Rates of biomass accumulation on different substrates were calculated by using FBA to optimize metabolic fluxes subject to a defined constraint on citrate synthase flux.
Additionally, optimizing the flux into the MG pathway improved 1,2-PDO formation at the expense of ethanol.
By optimizing metabolic flux and fermentation parameters, the engineered strains yielded 449 mg/L of total terpene, including 406 mg/L sesquiterpene with 100 mg/L caryophyllene and 10 mg/L caryolan-1-ol.
