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One PM patient with anti-PL-7 antibody did not develop ILD but had serositis.
One PM patient developed sepsis, which was recognised as a serious AE (SAE) related to the investigational drugs.
One PM completed the 2 months of 90 mg dose escalation; unfortunately, the last serum sample was not properly obtained.
One pM of the MAP can be estimated to yield the same signal as 1.56 pM (for 20-mer) to 5.0 pM (for 100-mer) of Aβ42 oligomers [ 33 ].
That is, the marginal gain (in terms of reducing the probability of failure of a PM) achieved by an increment of the number of VMs allocated to one PM decreases as the number of VMs in that PM approaches the number of possible failures, n.
None of the PM patients tested positive for anticentromere and antitopoisomerase 1, except one PM patient.
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Among 35 Na+ efflux genes, one PM-Na+/H+ antiporter gene (unigene798 or SOS1B) showed moderate transcript levels and two showed low transcript abundance.
France has only had one woman PM, the Socialist Edith Cresson, who served for less than a year.
She spent some time as a network radio producer in Washington DC, and later joined Radio 4's The World At One and PM.
Daniela Urzi, an Argentine model who is in the Hugo Boss fragrance campaign and is one of PM's investors, sat with a group of model friends.
For example, if the adversary may take full control of one particular PM, he could make it stop, which would be a crash failure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com