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One of the essential problems of our society is that we have a tendency, amid all the craziness that surrounds us, to lose sight of what is truly human in ourselves, and that includes our own individual needs — those very special, mostly nonmaterial things that would fulfill us, give meaning to our lives, enlarge us, and enable us to more easily embrace those around us.
One of the essential problems of implementing EU environmental policies encompassing the whole territory is that land-use policies are determined by Member States.
One of the essential problems in population genetics is determining how natural selection acts on the mutation rate of an organism during long-term evolution.
As Ms. Majorelle said, "A lot of people are talking about their carbon footprint, but I say, 'What about your concrete footprint?' Because that really is one of the essential problems with the urban environment, which is 80 percent concrete".
Helbing [2] offers a more detailed description of the potential restrictions of this approach, but one of the essential problems can be summarised as follows.
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As these cases illustrate, one of the essential design problems in generating (or identifying existing) populations for RPGC is to minimize the number of alleles segregating per locus the ideal number is two.
The increasing abundance of marker data amplifies one of the essential statistical problems in such studies: the number of potential explanatory variables represented by single markers is often larger than the number of observations in the sample studied, and some regularization is required to ensure the identifiability of the marker effects.
"The situation casts a light on the essential problems of Japanese society".
In the theory of differential equations, one of the essential and important problems is the initial value problem.
Fundamental to the Giuliani proposition is the idea of Giuliani as the essential problem-solver.
The essential problem was one of asymmetry: the enemy was nineteen Arab men in suits, holding commercial-airline tickets.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com