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However, since no adaptation is performed on rate changes, the policy presents worst dropping results than the ones acting on the on rate scenario.
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The debate on rate hikes is starting to open up".
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With negotiations over next year's premiums still under way, data on rate increases are mostly anecdotal.
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It's an add-on rate known as the guarantee fee.
However, the activation rate (turning-on rate) is about 10-fold faster than the inactivation rate.
On-rate experiments were performed by adding [2H]LA to cycloheximide-treated cells (Figure 2, left).
We systematically varied the dissociation constant and on-rate of the indicator (not shown).
Increasing the on-rate and off-rate of the indicator while maintaining the same Kd permitted better tracking of the actual free calcium, indicating that the primary cause of divergence was the low on-rate of the indicator.
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