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However, the generality of ON and OFF pathway asymmetries has not been tested.
Signal-to-noise ratios were weaker in the ASD group, particularly for the OFF pathway.
It was the first time the grieving parents had visited the unremarkable fenced off pathway, behind an auto repair shop and next to a busy highway, where their son died three months ago.
Similar(57)
These glutamatergic monopolar interneurons (GluMIs) do not receive direct photoreceptor input, and their light responses are strongly shaped by both ON and OFF pathway-derived inhibitory input.
The trade-off pathway most often observed reinforces the chosen visualization in terms of policy measures.
Politicians need not fear looking soft on border controls if they agree with a one-off pathway into citizenship for long-term migrants.
Mutations and off-pathway aggregation of proteins.
Alternative models for pausing invoke blockade events that precede translocation (on-pathway), enzyme backtracking (off-pathway), or isomerization to a nonbacktracked, elemental pause state (off-pathway).
Compartmentalization can prevent escape of volatile or toxic intermediates, prevent off-pathway reactions, and create private cofactor pools.
During expression of many recombinant proteins, off-pathway association of partially folded intermediates into inclusion bodies competes with productive folding.
Less optimized sequences dwell much longer in the unfolded state and/or off-pathway intermediates than do Gō-like models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com