Sentence examples for Notable difficulty from inspiring English sources

A notable difficulty is that a self-consistent and complete model of cosmic-ray propagation in the Galaxy has thus far been elusive.

It shows that about one-third of older adults who live in the community — nearly 13 million seniors — have a substantial need for assistance with daily activities such as bathing, eating, getting dressed, using the toilet, transferring in and out of bed or moving around their homes; about one-third have relatively few needs; and another third get along well on their own with no notable difficulty.

A notable difficulty in annotating genomic sequence is identifying the correct start codon in a gene.

This is a notable difficulty in understanding the roles of covarying groups of hydrocarbons as pheromones because these two CHCs were positively associated with male mating success [see Table 4 in 29] and it would have been useful to know if these two CHCs are also spatially differentiated on adult body parts.

Unfortunately this evolution as not without notable difficulties: issues surrounding the cost of products, the lack of support from large corporations and choice of platform resulted in substantial difficulties for educators in the assessment of appropriate technology.

In response to "current market concerns" over its exposure, the Credit Suisse Group -- which includes Switzerland's second-largest bank, Credit Suisse, and the insurance company Winterthur -- said it "has not experienced any notable difficulties".

Our main evaluation metric is area under the receiver operating characteristic curve (ROC AUC) adjusted to multi-class tasks since overall accuracy metric is associated with notable difficulties in the context of imbalanced data.

With regard to data sharing, there were notable difficulties in effecting an appropriate system since this was the first attempt to introduce two access levels (open-access and controlled-access levels) into informed-consent documents in Japan.

Due to the notable difficulties in aligning policy agendas, most interviewees mentioned that extra effort is required to develop a shared agenda.

For example, the question about walking ability is rated as follows: 0 = I can walk normally; 1 = I can walk with little difficulty; 2 = I can walk with notable difficulties; 3 = I can only walk a little; and 4 = I am unable to walk.

Our exclusion of children who fell more than 1.65 standard deviations below the mean on this measure suggests that our findings may not be as generalizable to children who may have been unlikely to cooperate with tasks and may experience notable difficulties with cognitive control.