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The development of genetic engineering technologies has today advanced to the point where the generation of high-affinity human antibodies against therapeutic targets is not a major hurdle.
The then Liverpool City Council leader Warren Bradley stated in November 2009 that a redevelopment of Goodison Park was his favoured option, and that relocation of the homes, infrastructure and businesses in streets adjoining the ground is "not a major hurdle".
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Similarly, the fact he has only one year outstanding on his Sunderland contract dictates that compensation does not constitute a major hurdle either.
Boosting that level probably won't be a major hurdle, notes Alan McHughen of the University of California, Riverside, who has worked on transgenic linseed.
Wilpon and his son, Jeff, the team's chief operating officer, have said that SNY, their cable sports network, is not for sale, a major hurdle to selling a stake in the team, sports bankers say.
However, this limitation has not proven to be a major hurdle to the quantitation of Aβ deposits in cortical gray matter, neither in the in vivo/postmortem cross-validation studies, nor in studies on the predictive value of the Aβ imaging findings, with regard to future cognitive decline.
I don't think that is a major hurdle.
The resulting 'data gap' has been identified by the WHO and other leading international organizations and advocacy groups as a major hurdle not only to assessing the population-level impact of ART but also to monitoring the effectiveness of HIV treatment programs [ 8, 9].
Brad Grey, an executive producer of HBO's "Sopranos" and a member of KCET's board since 1996, said the station's not-for-profit status remains a major hurdle in establishing ties with Los Angeles's top artists, no matter how charitably they might regard public television.
"Not only did we not abandon it, but we just got a major hurdle crossed".
If the two were merged, the combined group would control more than 90% of satellite-television services in the United States.That potential dominance remains a major hurdle, but not an insurmountable one, according to Charles Ergen, EchoStar's chairman.
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CEO of Professional Science Editing for Scientists @ prosciediting.com