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While emergency financing was not a major difficulty in the crisis, administrative procedures and perhaps culture, resulted in significant delays.
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The electronic platform Moodle was easy handling for the teaching staff, benefited from the IT back office of the University of Geneva, and did not represent a major difficulty for most of the students.
While the response rate was 94%%, overall satisfaction with QDU was high in 93 % of cases, repeated travel to hospital was not considered a major difficulty, and 84%% of patients would choose the QDU instead of hospitalization should a further diagnostic workup be required [ 21].
We're not talking about a major difficulty here, but just enough to induce a hiccup in comprehension, letting the physical facts of the painting preside.
But choosing which ICT systems they should invest in - some of which they may not yet fully understand - can be a major difficulty for teachers.
"I made the mistake of not devoting enough time to the last hour of the game," he writes in that same dissection of the game's pluses and minuses, and outlines the difficulties faced with selling a concept like this to publishers and players alike: "Explaining the concept of an original game with no real prior references is a major difficulty that must not be underestimated".
Despite the success of existing algorithms, a major difficulty that has not been sufficiently addressed is that of predicting rare labels.
"P14 now explains perfectly a major difficulty which we couldn't understand," Dr. McCormick said.
The polymerase chain reaction based-preemptive antifungal therapy creates a major difficulty, as this method is not yet established as a standard diagnostic for fungal infections.
A major difficulty is that American corporations are governed not only by federal law but also by the rules of the state in which they choose to incorporate.
A major difficulty is that both heat and work (not only heat) are involved.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com