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Next-generation sequencing methods provide an opportunity for molecular pathology laboratories to perform genomic testing that is far more comprehensive than single-gene analyses.
Next-generation sequencing methods remove these limitations by providing efficiently massive amounts of sequence data.
Next-generation sequencing methods represent the fastest growing technology worldwide, with ever decreasing cost per analysis (http://www.genome.gov/sequencingcosts/).gov/sequencingcosts/
Next-generation sequencing methods have contributed to rapid progress in the fields of genomics and population genetics.
Profaizer, T. et al. HLA genotyping in the clinical laboratory: comparison of next-generation sequencing methods.
CPSGs are designed to work across most next-generation sequencing methods, platforms, and data analysis pipelines.
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Because of the high read depth generated, next generation sequencing methods provide an opportunity to interrogate variant data, including the presence of low-level resistance mutations.
The genome sequences of the type 2 strains FH and 309 were completed using next generation sequencing methods (Roche 454 sequencers) [ 19, 20].
At present, however, reading DNA sequences from genomes using current next generation sequencing methods is still a costly endeavor restricted to well-equipped laboratories.
Recent years have seen the complex genetic architecture of the disease being progressively unraveled with advancements in gene finding technology and next generation sequencing methods.
Information on rice splicing may be extracted from tiling array data [21, 22], which provides complete information regarding alternatively spliced transcripts, or next generation sequencing methods.
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