Sentence examples for Next-generation sequencing approaches from inspiring English sources

Next-generation sequencing approaches are characterized generally by the massively parallel production of short sequences, in which multiple DNA fragments are generated simultaneously and in sufficient quantity to redundantly represent every base in the target genome.

Next-generation sequencing approaches and other STR assays rely on a limited number of PCR amplicons, typically in the tens.

Next-generation sequencing approaches have also started to provide important insights.

Next-generation sequencing approaches require bulk processing of DNA fragments and massively parallel sequencing.

Next-generation sequencing approaches were used to identify microsatellite loci and design primers.

Next-generation sequencing approaches have identified non-coding RNAs that represent a novel mechanism to orchestrate gene expression programs.

Marrying next generation sequencing approaches allowed us to generate a list of genes differing at the transcriptional and sequence levels in strains with contrasting transmission status.

With the advent of next generation sequencing approaches, however, new insights can be generated into the genetic architecture of susceptibility [ 23, 30].

Even in model systems where next generation sequencing approaches have been used extensively, we are far from a general understanding of the underlying architecture of resistance and susceptibility.

In the past several years, rare disease consortia have embarked on the discovery of disease-causing genes for Mendelian diseases using next generation sequencing approaches.

Most importantly, the accuracy of the method in quantifying locus-specific methylation was comparable to both fluorescence-based and Next Generation Sequencing approaches.