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It is staring us in the face that national wealth must be expended, or we won't get out of the economic stall caused by the negative interplay of these two fundamentally sour markets.
This, in turn, might further promote the previously mentioned negative interplay between the RAAS and FGF-23 in CS.
In the negative interplay case, acetylation of β-catenin at K19 and 49 by PCAF blocks β-catenin ubiquitination thereby stabilizing β-catenin [ 104].
The best studied PTM crosstalk in Wnt/β-catenin pathway is the positive and negative interplay between PTMs on β-catenin: the sequential phosphorylation and ubiquitination of β-catenin [ 12, 14, 123] and competition between acetylation and ubiquitination of overlapping lysine residues on β-catenin [ 104].
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This positive-negative interplay is central to the cut-out sculptures of the early 1990's.
The complex interplay of negative and positive aspects of religion, gender, and development was very much on display.
The menstrual cycle is regulated by interplay of negative and positive feedback loops.
Ultimate angiogenic outcomes depend on the dynamic equilibrium between positive and negative regulators and the interplay among their signal transduction pathways, not on a single discrete pathway.
Thus, a complex interplay between negative regulation of hESCs and adult muscle stem cells by the aged niche, and positive regulation of the host's regenerative responses by hESCs will likely determine the success of hESC-based cell-replacement therapies in the old.
Negative consequences arise from the interplay between resilience (the capacity to adjust and recover from a hazard) and vulnerability (the susceptibility to damage from a hazard) (Paton [2005]; UNISDR [2009]).
There is an interplay between the negative effects of contrast media on renal hemodynamics and on tubular cell function that leads to activation of renin-angiotensin system and increased production of reactive oxygen species (ROS) within the kidney.
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