Sentence examples for Multivariate assay from inspiring English sources

Multivariate assay approaches for lupus, RA, and other rheumatic diseases are being investigated.

We describe the development and preliminary evaluation of a serum-based multivariate assay for ovarian cancer.

They are many fibrosis biomarkers and the two most investigated and validated biomarkers are the FibroTest (FT), a serum in vitro multivariate assay (FibroTest®, Biopredictive, Paris, France; FibroSURE® in the USA, LabCorp, Burlington), and the Fibroscan [Echosens, Paris, France], a measure of liver stiffness (LSM) using elastography [ 4- 9].

Multigene biomarker measurements are at the forefront of a new class of medical devices using in vitro diagnostic multivariate assays, such as MammaPrint and Oncotype Dx in the area of breast cancer prognosis [ 11].

The F.D.A. is calling these tests "multivariate index assays".

Multivariate genomic assays that take input from ER and human epidermal growth factor receptor 2 (Hexpressionssion as well as from a number of proliferation-related genes can stratify ER-positive cancers into low and high risk prognostic groups objectively and this information is additive or complementary to prognostic risk based on tumor size and nodal status.

Furthermore, the guidance said the FDA will focus initially on high complexity testing assays, such as Multivariate Index Assays [ 16], assays which measure multiple analytes and use mathematical algorithms to determine the clinical significance of the test result.

The US Food and Drug Administration FDAA) has used the term ' in vitro diagnostic multivariate index assay' (IVDMIA) to describe laboratory assays that combine the values of multiple individual tests into a single result or index that is not transparent and cannot be easily verified by the provider [ 10], and the cluster analysis by the authors fits into that category.

The purpose of this study was to investigate the relationship between imaging and the multivariate index assay (MIA) in the prediction of the likelihood of ovarian malignancy before surgery.

To determine the impact on referral patterns of using a Multivariate Index Assay, CA125, modified-American College of Obstetricians and Gynecologists referral guidelines, and clinical assessment among patients undergoing surgery for an adnexal mass after initial evaluation by nongynecologic oncologists.

We sought to analyze the effectiveness of a multivariate index assay (MIA) in identifying early-stage ovarian malignancy compared to clinical assessment, CA 125-II, and modified American Congress of Obstetricians and Gynecologists (ACOG) guidelines among women undergoing surgery for an adnexal mass.