Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
Most substantially
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "Most substantially" is correct and usable in written English.
It can be used to emphasize the most significant or important aspect of a discussion or argument. Example: "Most substantially, the research indicates a direct correlation between diet and mental health."
✓ Grammatically correct
Science
News & Media
Encyclopedias
Wiki
Alternative expressions(20)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
46 human-written examples
Most substantially, SB-431542 exposure to epithelial-like CD44posCD24pos cells blocked their ability to give rise to mesenchymal, vimentin positive progeny.
Science
Here the marble sculptures most substantially embody his deceptively ingenuous sensibility.
News & Media
Several countries made pledges to the fund, including most substantially, a pledge of $1bn from France.
News & Media
Art exhibitions and cultural festivals much enriched Australian life, most substantially in the smaller capitals.
Encyclopedias
The wave of homicides subsided most substantially in New York, but violence slid in most cities.
News & Media
But perhaps the most substantially Angeleno thing about Chelsea is not the mindset, but the extravagance it affords in terms of space.
News & Media
Human-verified similar examples from authoritative sources
Similar Expressions
14 human-written examples
This leaves most convertibles substantially out of the money, meaning the common is well below where conversion would make sense.
News & Media
None of the creatures in its exhibits is bigger than an ant, and most are substantially smaller — zipping water fleas, invincible tardigrades, green algae, and innumerable bacteria.
News & Media
Under current guidelines, the maximum amount an author can receive in any one year is £6,600, but most receive substantially less.
News & Media
Most are substantially larger than Earth, but 10 are about the same size as our home planet.
Science & Research
Therefore, the diversification of the extant Eurasian beaver lineages started most likely substantially earlier than previously estimated.
Science
Expert writing Tips
Best practice
Use "most substantially" to emphasize the most significant aspect of a change, contribution, or difference. It adds a layer of precision compared to simpler adverbs like 'mostly'.
Common error
Avoid using "most substantially" in casual conversation or informal writing. Opt for simpler alternatives like "mainly" or "primarily" to maintain a natural tone.
Source & Trust
82%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "most substantially" functions as an adverbial modifier, emphasizing the degree or extent to which something is affected. As confirmed by Ludwig AI, it is correctly used to highlight the significance of a change or contribution.
Frequent in
Science
52%
News & Media
32%
Wiki
8%
Less common in
Encyclopedias
4%
Formal & Business
0%
Social Media
0%
Ludwig's WRAP-UP
In summary, the phrase "most substantially" functions as an adverbial modifier used to emphasize the degree or extent of an action, change, or effect. Ludwig AI confirms its grammatical correctness and appropriateness in formal contexts, particularly within scientific and news-related domains. While it’s a valuable tool for adding precision to writing, it should be used judiciously in less formal settings. Alternatives like "most significantly" or "primarily" may be more suitable in casual conversation. With a common frequency and clear purpose, understanding the nuances of "most substantially" can significantly enhance writing clarity and precision.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
Most significantly
Emphasizes the importance or consequence to a greater extent.
To the greatest extent
Highlights the maximum degree to which something occurs.
Primarily
Focuses on the main or chief aspect.
Notably
Draws attention to a particular point of significance.
Mainly
Indicates the principal component or action.
Predominantly
Highlights the prevailing or dominant aspect.
Principally
Stresses the primary reason or cause.
Particularly
Singles out a specific element for emphasis.
In particular
Emphasizes a specific aspect among others.
Above all
Indicates the highest priority or importance.
FAQs
How to use "most substantially" in a sentence?
"Most substantially" is typically used to emphasize the degree or extent to which something is affected or changed. For example, "The budget was "most substantially" reduced in the education sector."
What can I say instead of "most substantially"?
You can use alternatives like "most significantly", "to the greatest extent", or "primarily" depending on the context.
When is it appropriate to use "most substantially"?
Use "most substantially" in formal writing or when you want to emphasize the magnitude of an effect or change. It's suitable for academic papers, reports, or formal presentations.
What's the difference between "most substantially" and "significantly"?
"Most substantially" implies a greater degree or impact compared to "significantly". While both indicate importance, "most substantially" suggests a more pronounced or considerable effect.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
82%
Authority and reliability
4.5/5
Expert rating
Real-world application tested