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For expectant mothers, the risk is the most grave.
This is not the first health issue that Justice Ginsburg has faced, nor the most grave.
This is the third -- and probably the most grave -- indictment against Mr. Milosevic.
Those who fraudulently interfere are committing a most grave offence against the body politic.
The archbishop added that as an excommunicated priest celebrating Mass, Mr. Bozek would commit "a most grave sin".
There is no clear limiting principle on the idea that corporations are religion-bearing entities whose beliefs cannot be infringed under all but the most grave circumstances.
"It certainly is the most serious case of a possible spill in the history of the Tuscan islands, one of the most grave in the Mediterranean," he said.
A cardinal can be deprived of his rank for what the Church calls "the most grave reasons;" he may, if he wishes, resign.
The N.B.A. is confronting a number of serious issues in the Gilbert Arenas saga, with firearms possession the most grave concern.
It described the issue as the most grave human rights issue in the world and made 140 recommendations for preventing and addressing it.
Raising tariffs is the solution, even if it adds temporarily to the inflation figures.The final reason to worry is also the most grave.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com