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Women who have mutations that modify risk may well be interested in tailoring their preventive medical management to an adjustment in risk.
Finding environmental factors or lifestyle exposures that modify risk in this genetically susceptible group could shed new light on biological pathways amenable to pharmacological intervention.
OBJECTIVE: Individuals with type 2 diabetes have high risk of late-life cognitive impairment, yet little is known about strategies to modify risk.
We measure risk-related private information and investigate its importance in a setting where individuals are able to modify risk ex-ante through costly effort.
While treating the stress fracture, it is important to evaluate and modify risk factors that may predispose the athlete to future injuries, including anatomic abnormalities, biomechanical forces, hormonal imbalances, and nutritional deficiencies.
Interventions that either modify risk or reduce the development of early disease could delay the onset of dementia or reduce the rate of cognitive and functional decline.
Studies of discordant twins suggest that dementia risk might be altered through environmental pathways in early adulthood; the extent to which particular genes modify risk or benefits of potential environments is less understood, from a twin perspective, to date.
In conclusion, effective upstream prevention programs have been identified that modify risk and protective factors for adolescent suicide, and key knowledge breakthroughs can jump-start progress in realizing the suicide prevention potential of specific strategies.
Availability of 1-C units may modify risk.
Recent large-scale genome wide association studies (GWAS) have identified more than twenty loci that modify risk for AD.
These results are consistent with the view that individual genotypes modify risk by predisposing to substantially different distributions of AD onsets.
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