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Bosniak IIF lesions vary in appearance: (1) BIIF lesions with minimal findings close to category II in complexity and (2) BIIF lesions that are closer to category III in complexity.
M.A. Bosniak has recently suggested that BIIF cysts with minimal findings only need follow-up for 1 2-years, whereas more complex BIIF cysts should be followed for a longer period (e.g., 3–4 years or longer) [1 2-years
Mice with high or low levels of the protein had minimal findings – at most, steatosis without inflammation.
Recently, a patient with an absence of p85α, resulting in an early and severe defect in B cell development accompanied with agammaglobulinaemia, but with minimal findings in other organ systems was reported [ 19].
Lack of studies currently using the Freedom of Information Act and there is an element of publication bias within the available literature, as those that had minimal findings are unlikely to achieve publication.
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Despite the dramatic neurologic manifestations, minimal histopathologic findings in CNS lupus are typical, with apparently normal findings or nonspecific changes in the brain predominating.
In an article for Psychiatric Times, Jones reviewed outbreaks of mass psychogenic illness and compared them with incidents of confirmed toxic exposures; he "was unable to identify any outbreaks of acute illness from toxic exposures, with minimal physical findings, where the cause was not quickly apparent to investigators".
STEM clustering in bystanders suggested only one biologically significant cluster with minimal biological findings in other clusters.
Some centres advocate surgical resection for most lesions, whereas others favour serial follow-up[ 12 15 ], especially in cases with normal clinical laboratory analyses and minimal radiological findings, or in patients with significant comorbidities[ 16, 17 ].
More importantly, using a bleeding model that closely mimics the clinical morbidity of hemophilic arthropathy, mice that received the scAAV8.FIXR338L vector developed minimal histopathological findings of synovitis after hemarthrosis, when compared with mice that received identical doses of wild-type FIX vector.
The aim of the classical VRP is finding a set of routes at a minimal cost (finding the shortest path, minimizing the number of vehicles, etc).
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CEO of Professional Science Editing for Scientists @ prosciediting.com